Khanna died of advanced bladder cancer on Thursday morning, said Tushar Pania, from the HN Reliance Foundation and Research Centre in Mumbai.
Dubbed Bollywood’s “Original heartthrob,” Khanna had reportedly been battling cancer for several years.
In a career spanning over four decades, Khanna acted in over a 100 films.
Despite his move into politics, Khanna continued to act with his latest film being 2015’s “Dilwale,”.
Khanna is survived by his second wife Kavita, his children Rahul, Akshaye, Sakshi and Shraddha.
Rahul and Akshaye are both also actors; his son Rahul Khanna is best known to international audiences for playing Yousaf Rana in the spy thriller television series, “The Americans.”